Chrono Slicers are the time-manipulating mechanisms set alongside Laser Barriers in Devil May Cry 4. They are scattered throughout the Order's HQ and require the Key of Cronus to operate. However, the Key of Cronus which Dante and Nero find is still in its developmental stage, limiting the Chrono Slicer's abilities. However, in the Security Corridor, a larger Chrono Slicer is installed, allowing a much longer lasting slowdown ability.
The Chrono Slicers do not work without the Key of Cronus. In its time-slowing ability, all entities except the possessor of the Key of Cronus slow down in motion. This is an advantage to the player if activated in the middle of combat.
- The grayscale effect that filters the screen during the activation of the Chrono Slicer is called the "Old Movie Filter". It has been used in making films in the early 1900s.