| I should have been the one to fill your dark soul with liiiiiiiiiiight! |
Handguns have the lowest damage, which is compensated by their high rate of fire and great mobility. Most of their attacks are intended for mid/close range. Their attack can be charged up to three levels (if skills are bought), each one requiring more time to charge it up. The special meter shows how much time it takes to charge and what level of charge you are at.
- Hollow Point, Napalm Shot and Explosion Shot bear strong resemblance to Blue Rose's Charged Shot, Charged Shot 2 and Charged Shot 3.
|Agnus - Credo - Dante - Gloria - Kyrie - Lady - Nero - Sanctus - Trish|
|Bael & Dagon - Berial - Containment Room - Echidna - The Savior|
|Alto Angelo - Assault - Basilisk - Bianco Angelo - Blitz - Chimera Seed & Chimera - Cutlass - Fault - Frost - Gladius - Mephisto & Faust - Scarecrow|
| Nero: Blue Rose - Devil Bringer - Red Queen - Yamato|
Dante: Ebony & Ivory - Coyote-A - Rebellion - Gilgamesh - Pandora - Lucifer - Yamato
|Buster - Dark Slayer Style - Gunslinger Style - Royalguard Style - Swordmaster Style - Trickster Style|
|Dante's Office - Fortuna - Fortuna Castle - Mitis Forest|