Sometime before their eighth birthday, Eva gave Dante and Vergil each a half of the Perfect Amulet. Around the same time, Sparda disappeared, and Eva and the twins were left alone. Some point after Sparda's death, when the twin's turned eight, Vergil, Dante, and their mother were attacked by revenge-seeking demons, who hoped to harm Sparda's loved ones. Eva was killed, while the brothers survived. However, the twins were separated, and Dante believed Vergil to be dead.
Sometime prior to the events of the Temen-ni-gru, Vergil had been traveling the world, looking for information about his father, Sparda. It was during this time that he visited the city of Fortuna to investigate the Order of the Sword. Upon his arrival into the city, Vergil wondered why they worship a demon like Sparda as a god. As he pondered, a horde of Scarecrows surround him, but Vergil dispatches them with little effort. After that brief encounter, Vergil then continued deeper into Fortuna, intending to learn more about the Order and their intentions. As he walked, he passed by a group of pedestrians, with a woman in a scarlet red dress taking notice of him as he walked away. After finishing his investigation of the Order's plan, Vergil soon leaves the town pondering whether or not one can call them misguided for their worship. As he walks away, he vows that one day the Order will know the true power of the son of Sparda.
Arkham helps Vergil to break the first seven seals Sparda cast upon the Temen-ni-gru, and then directs him to the Forbidden Land at the base of the tower. Vergil is later seen alongside Arkham at the top of the emerging tower. When the Hell Vanguard they sent to kill Dante returns, having failed its task, Vergil immediately dispatches it.
Vergil waits at the top of the tower for Dante, and at one point dispatches Arkham to eliminate Lady. When Dante reaches the peak of the tower, the two banter and then ferociously battle. Vergil emerges victorious, and takes Dante's half of the Perfect Amulet as his prize. Though Dante's Devil Trigger begins to manifest and Vergil prepares to fight him again, Arkham urges him to ignore Dante because "[they] already have all [they] need". The two then jump off the tower to reenter the Forbidden Land.
As Vergil and Arkham approach the final door to the Lair of Judgement, Vergil reveals his knowledge of Arkham's betrayal, and deals him a mortal blow. He then enters the chamber and commences the ritual to open the gate to the demonic world. During this ritual, he is momentarily interrupted by a blinded Beowulf, who has mistaken him for Dante. However, Vergil quickly vivisects the devil, and takes his soul as a Devil Arm.
While Dante was hurrying up to the final seal, Vergil had no luck on unlocking the seal, and was later interrupted by Dante. The twins engaged another fight which was interrupted by Lady causing the battle to end in a tie. Both demonic brothers are equally wounded, and Jester makes his appearance by announcing that everybody has served their role nicely. Jester later turned back and forth between Arkham and Jester, explaining why Vergil's ritual was incomplete, and why Vergil had failed against Dante and Lady. Arkham completes the ritual, and then plays with the three warriors while waiting for the tower to activate. Once it does, he knocks them off the ascending platform, wherein Vergil falls into an abyss.
Later, after Dante enters the Netherworld, Vergil is seen passing through the Divine Library, with Lady still huddled up, wounded and in grief, after her battle with Dante. She hears his footsteps and looks up to see who it was, but by that time, he had already gone through the door that Dante took. Vergil later interrupts Dante's fight with the ascended Arkham, and the twins finish Arkham off together. However, Vergil has not given up his goal of obtaining the Force Edge, and the twins are again forced to fight. Though Dante is able to defeat Vergil, he cannot convince him to return to the Human World. Vergil lets himself fall even deeper into the Netherworld.
In the epilogue, Vergil is seen in the Room of Fallen Ones, while three glowing orbs approach. Vergil recognizes the approaching devil, and prepares to defeat him, remarking "If my father did it, I should be able to do it too." However, in his weakened state he is defeated and corrupted into becoming Nelo Angelo.
Vergil later reappears at Mallet Island, though as Nelo Angelo, he is unrecognizable to Dante. Eventually, Dante does notice his honorable persornality, and questions why such a person would serve Mundus.
Nelo Angelo first appears to Dante as a reflection in the bedroom's mirror, from which he emerges and challenges Dante to a duel in the castle garden. They fight, and Nelo Angelo manages to pin Dante to a wall. However, Dante's amulet slips out just as Nelo Angelo attempts to deliver the killing stroke, and the sight of it awakens Vergil's memories, causing Nelo Angelo pain and forcing him to flee. He returns to challenge Dante in the garden near the Colosseum, but is defeated and again forced to flee. He finally returns one last time in a hall in the warped castle, where Dante questions the knight's loyalty to Mundus, and he shows his true face (yet Dante shows indifference). He challenges Dante one last time, and though he has been granted with new powers, Dante defeats him and he screams in pain as he disappears in a torrent of blue flames, leaving his half of the amulet. By looking at the amulet, Dante has a flashback and realizes that Nelo Angelo is Vergil.
Sometime after his death as Nelo Angelo, his remains were used to create the Bianco & Alto Angelos.
- NOTE: The following section contains information that appears in the Devil May Cry Volume 1, which has been classed as non-canon with the original Devil May Cry mythology and takes place in an alternate timeline.
A mysteriously bandaged man sporting a green suit, he is looking to join a popular group of mercenaries. He even goes as far as killing a harmless man looking for information on him to keep it a secret. Gilver is initiated into the group after picking a fight with Tony Redgrave which eventually becomes a vodka drinking contest. Unlike Tony, Gilver can't hold his liquor and passes out nearly immediately and gets mugged because of the guild's tradition of "whoever passes out first pays for the drinks". Understandably, Gilver expresses his dislike of for alcohol for the rest of the novel.
Although older than his DMC3 incarnation, he still retains his chilling and calm attitude. It is stated that his stare will even give the meanest of men goosebumps, however everyone envies his extraordinary strength and skills with his slim katana. He took on any high-paying jobs, unlike Tony, and would pay for the drinks at Bobby's Cellar (which is the novel's the "hang out" bar for mercenaries) when he returned from his jobs thus earning him quite a reputation even though he was taking all the good jobs away from them.
This generosity was a clever ruse, as by earning the trust of the guild he then proceeded to feed them to the demons he released after slowly but surely unleashing the wrath of the Underworld back onto the Human World.
His evil scheme was to allow the darkness to distort and manifest all of the Human World so that he could release his true demonic powers. He was able to read his brother's fighting style even after the sword his brother wielded had awakened. Gilver tried to cut out Dante's heart but he failed thanks to their mother's amulet. He is fatally wounded after Dante opens fire on him with his new guns: Ebony & Ivory. It is then that the bandages covering his face fall off, revealing to his little brother that his opponent is his own twin. He then fades away along with the demonic powers that tried to consume the Human World a second time.
At least one year before the events of Devil May Cry 3, Arkham finds Vergil searching for a book in his library, and tells him about the legend of the Temen-ni-gru. Vergil endorses Arkham's plan to raise the Temen-ni-gru. Arkham reveals that they must undo a number of "seals" as the first step. These seals are, in fact, fallen angels representing the seven deadly sins, and they must be given their names in order for the seals to be undone. While Arkham searches for the location of each seal, Vergil resides in his mansion, along with Alice. However, he wanders through the town at one point, and is confused with Dante by Enzo Ferino. The revelation that Dante lives within the city seems to excite Vergil.
After conversing with Dante, exchanging several threats of mortal injury with him in the process, Vergil reveals his plan of raising the Temen-ni-gru, thus opening the gate of the demon world. When Dante declares his intent on stopping Vergil, Vergil then proceeds to taunt Dante by showing him the half of the amulet that Alice stole earlier, prompting him to attack. However, after a quick battle, in which Vergil trounces Dante, Vergil throws his brother’s half back to him; Vergil then taunts Dante again, stating that he could retrieve the amulet from him whenever he wanted. This chapter concludes with Arkham preparing to start the ritual to raise the Temen-ni gru.